In Woman Or Merry Man With Sexual of the Shingles, Aciclovir does Not Prevent Aquisition HIV

June 24, 2008

Aciclovir, Antivirusnoe medicine, does not reduce the issue HIV-1 in gal or man, who have a shingles sexual, which has a sex By the side of man, according to author of the Article released in June 20, 2008 in Lancet.

The Simplex virus of the Shingles type-2 infections (HSV-2), most general reason of the shingles sexed, is bound two on three-pack the increased risk to infections HIV-1. To help to define the species to this assotiations, Dr. Connie Celum, University Washington, Seattle, USA, and colleagues, studied effects of the suppression HSV-2 with aciclovir put on HIV-1. This was made using gainsaying HIV-, positive women(woman)s HSV-2 in Africa and man, who have a sex in company man (MSM) with places in Peru and USA.

In mixed, operated by phase III test, participants whir nominated to be control 400mg aciclovir (1,637 patients) or (1,640 patients) during 12-18 months. Followups Were Executed monthly to study the dispensation a medicine analysis, execute the counsel of the adherence, tell of the pill (itself qualified), and reduction counsel of the risk. Each threesome months, examinations sexual and test retrovirus were executed. The Tested results were an Contagion HIV-1 and and canker sexual HSV-2.

The Participants were 1,358 womans and 1,814 MSM comprised of assay: 1,581 in set apart aciclovir and 1,591 in controlling gruppe. incidence HIV-1 was not worlds a different between group. This reported, incidence gentical cankers reducted to 47% in group aciclovir, and 65% cankers sexual confirmed to be due to HSV-2. Was Not no serious disadvantage Adventure in recorded medication.

In inference, authors indicate that aciclovir has y no influence in fact of the issue HIV-1 in this population. “Our results show that repressing psychotherapy with principle dose aciclovir not efficient in reduction of aquisition HIV-1 inn HSV-2 seropositive woman and MSM. The New strategies - it be requirement to break the interaction between HSV-2 and HIV-1.” Additionally, speak, these futher studies must be executed to induct independently this defect to efficiency is due to absorptions medicine and metabolism, clinical answer of the cankers sexual in medication, or firm answer firm sexual after HSV-2 will is actuated.

The Professor Ronald Gray and Weaver Professor Maria, John Hopkins University, Baltimore, MD, USA, accompanying commentary in which they discuss if transactions sexual sent infection must be modern for prohibiting HIV in negative population HIV. “saint Henry Huxley commented that ‘ big tragedy of the science - a murder of the beautiful theory At ugly fact.’ The Time to revalue the hypothesis and to adjust the stratagem of the prevention accordingly.”

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